Welcome to the BMTInfonet Drug Database

This guide lists many of the drugs bone marrow, stem cell and cord blood transplants patients receive during treatment. It explains why they are used and some, but not allAcute lymphoblastic leukemia., of the possible side effects.

This guide should not be used as a substitute for a detailed discussion with your doctor and pharmacist about drugs you are being given. If you experience any side effect after taking the drug, even if they are not noted below, consult your doctor immediately.

Some of the drugs in this guide are also used outside the transplant setting. The descriptions of the drugs in this guide pertain only to their use in bone marrow, stem cell or cord blood transplantation.

If you are searching for a drug used by transplant patients and survivors that is not in this database, please contact us at drugdata@bmtinfonet.org.

This database was compiled under the direction of pharmacists knowledgeable about transplantation, but should not be construed as medical advice. Consult your doctor for information about how each drug might affect you.

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Budesonide EC


Trade Names: 
Entocort EC®

Possible Uses: 
Use to prevent/treat graft vs host disease of the GI tract

Special Notes: 
available as a capsule

Drug Interactions: 
grapefuit juice or grapefruit should be avoided when taking these capsules

Possible Side Effects: 
headache, nausea, diarrhea,
Last updated on 02/01/2010

Busulfan


Trade Names: 
Myleran®
Trade Names: 
Busulfex®

Possible Uses: 
Chemotherapy drug for patients with myelogenous leukemia. Used in larger doses as a conditioning agent in AML patients.

Special Notes: 
Can be given IV or orally.

Possible Side Effects: 
Decreased blood counts, nausea, diarrhea, vomiting, temporary hair loss, increase in liver function tests, infertility, cessation of menstruation, dark spots on skin, itching, cataracts, seizures, lung damage. Larger doses may cause seizures.
Last updated on 02/01/2010

Carmustine


Trade Names: 
BiCNU®

Alternate Names: 
BCNU

Possible Uses: 
Chemotherapy drug. Treatment of some brain tumors, multiple myeloma, Hodgkin's disease, non-Hodgkin's lymphomas, part of some conditioning regimens for bone marrow transplant

Drug Interactions: 
Cimetidine, digoxin, echinacea

Possible Side Effects: 
Nausea, vomiting, temporary hair loss, mouth sores, redness in eyes, vision problems, breathing difficulties, yellowing of skin or eyes, reversible kidney disorder, decreased coordination.
Last updated on 02/01/2010

Clarithromycin


Trade Names: 
Biaxin®

Possible Uses: 
Treat or prevent infection.

Special Notes: 
Finish all medication. Do NOT skip doses

Drug Interactions: 
Interferes with some drugs metabolized by the liver. May be toxic to heart when used with quinidine. Avoid calcium supplements, antacids, and dairy products one hour before or two hours after taking.

Possible Side Effects: 
Diarrhea, abdominal pain and cramping, nausea, vomiting, liver dysfunction, heartbeat irregularity, rash.
Last updated on 02/01/2010

Diphenhydramine


Trade Names: 
Benadryl®

Possible Uses: 
Decrease allergic reaction from some medications, decrease itching, dry up mucous, decrease sinus drainage. This is an anti-histamine

Possible Side Effects: 
Rash, sweating, chills, dry mouth, nose and throat, low blood pressure, head ache, heart palpitation, sedation, drowsiness, dizziness, decreased coordination.
Last updated on 02/01/2010

Trimethoprim/sulfamethoxazole


Trade Names: 
Bactrim®
Trade Names: 
Bactrim DS®
Trade Names: 
Septra®
Trade Names: 
Uroplus®

Alternate Names: 
TMP/SMX

Possible Uses: 
Prevent or treat bacterial infections.

Possible Side Effects: 
Rash, nausea, vomiting, diarrhea, stomach upset, decreased blood counts, change in kidney or liver function. If patient is allergic, may cause breathing difficulties, swelling of face, throat or lips.
Last updated on 02/01/2010