Welcome to the BMTInfonet Drug Database

This guide lists many of the drugs bone marrow, stem cell and cord blood transplants patients receive during treatment. It explains why they are used and some, but not allAcute lymphoblastic leukemia., of the possible side effects.

This guide should not be used as a substitute for a detailed discussion with your doctor and pharmacist about drugs you are being given. If you experience any side effect after taking the drug, even if they are not noted below, consult your doctor immediately.

Some of the drugs in this guide are also used outside the transplant setting. The descriptions of the drugs in this guide pertain only to their use in bone marrow, stem cell or cord blood transplantation.

If you are searching for a drug used by transplant patients and survivors that is not in this database, please contact us at drugdata@bmtinfonet.org.

This database was compiled under the direction of pharmacists knowledgeable about transplantation, but should not be construed as medical advice. Consult your doctor for information about how each drug might affect you.

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Alemtuzumab


Trade Names: 
Campath®

Possible Uses: 
Approved for B-Cell chronic lymphocytic leukemia. Also used for T-cell lymphoma and leukemia.

Special Notes: 
Can be given by IV infusion and SQ injection

Drug Interactions: 
echinacea

Possible Side Effects: 
Low blood pressure, edema, fever, chills, fatigue, headache,rash, neasuea, vomiting, diarrhea, mucositis. Lymphopenia is significant as well as neutropenia, anemia, and low platelets. Rigors, cough, and infections can occur.
Last updated on 02/01/2010

Calcium Acetate


Trade Names: 
PhosLo®

Possible Uses: 
Taken with meals to lower phosphorous levels in blood. If taken between meals it is used to increases calcium.

Special Notes: 
Should be taken 1-2 hours after other medications.

Drug Interactions: 
Many interactions including antibiotics and mycophenolate, check with your pharmacist.

Possible Side Effects: 
Diarrhea or constipation, vomiting, flatuence.
Last updated on 02/01/2010

Calcium Carbonate


Trade Names: 
Caltrate®
Trade Names: 
Os-Cal®
Trade Names: 
Titralac®
Trade Names: 
Tums®

Possible Uses: 
Increase calcium, decrease phosphorous, acts as an antacid.

Special Notes: 
Should be taken 1-2 hours after other medications.

Drug Interactions: 
Many interactions including antibiotics and mycophenolate, check with your pharmacist.

Possible Side Effects: 
Diarrhea,vomiting, constipation or flatulence.
Last updated on 02/01/2010

Carboplatin


Trade Names: 
Paraplatin®

Alternate Names: 
CPP
Alternate Names: 
CBDCA

Possible Uses: 
A chemotherapy drug.

Special Notes: 
Derived from the metal platinum.

Possible Side Effects: 
Decreased blood counts, nausea, vomiting, diarrhea, loss of appetite, metallic taste in mouth, mouth sores, temporary hair loss, decreased potassium and magnesium in blood, numbness or tingling in hands and feet, ringing in ears, hearing damage, decreased kidney function. Rarely, allergic type reaction causing breathing difficulties with swelling of mouth and tongue.
Last updated on 02/01/2010

Carmustine


Trade Names: 
BiCNU®

Alternate Names: 
BCNU

Possible Uses: 
Chemotherapy drug. Treatment of some brain tumors, multiple myeloma, Hodgkin's disease, non-Hodgkin's lymphomas, part of some conditioning regimens for bone marrow transplant

Drug Interactions: 
Cimetidine, digoxin, echinacea

Possible Side Effects: 
Nausea, vomiting, temporary hair loss, mouth sores, redness in eyes, vision problems, breathing difficulties, yellowing of skin or eyes, reversible kidney disorder, decreased coordination.
Last updated on 02/01/2010

Caspofungin


Trade Names: 
Cancidas®

Possible Uses: 
Prevention or treatment of fungal infections.

Special Notes: 
Given IV

Possible Side Effects: 
Diarrhea, rash, hypotension, and a rare but serious allergic reaction.
Last updated on 02/01/2010

Cefazolin


Trade Names: 
Ancef®
Trade Names: 
Kefzol®

Possible Uses: 
Prevent or treat bacterial infections.

Possible Side Effects: 
Diarrhea, nausea, vomiting, or rash. If patient is allergic, may cause rash, swelling, breathing difficulties.
Last updated on 02/01/2010

Cefepime


Trade Names: 
Maxipime®

Possible Uses: 
Prevent or treat bacterial infections.

Possible Side Effects: 
Diarrhea, nausea, vomiting, pain and inflammation at injection site, fever, headache, rash, temporary increase in liver function tests, blurred vision. If patient is allergic, may cause rash, swelling, or breathing difficulties.
Last updated on 02/01/2010

Cefoperazone


Trade Names: 
Cefobid®

Possible Uses: 
Prevent or treat bacterial infections.

Possible Side Effects: 
Diarrhea, nausea, vomiting, pain and inflammation at injection site, fever, headache, rash, temporary increase in liver function tests, blurred vision. If patient is allergic, may cause rash, swelling, or breathing difficulties.
Last updated on 02/01/2010

Cefotaxime


Trade Names: 
Claforan®

Possible Uses: 
Prevent or treat bacterial infections.

Possible Side Effects: 
Diarrhea, nausea, vomiting, pain and inflammation at injection site, fever, headache, rash, temporary increase in liver function tests, blurred vision. If patient is allergic, may cause rash, swelling, or breathing difficulties.
Last updated on 02/01/2010

Ceftazidime


Trade Names: 
Ceftaz®
Trade Names: 
Fortaz®
Trade Names: 
Tazidime®

Possible Uses: 
Prevent or treat bacterial infections.

Possible Side Effects: 
Diarrhea, nausea, vomiting, pain and inflammation at injection site, fever, headache, rash, temporary increase in liver function tests, blurred vision. If patient is allergic, may cause rash, swelling, or breathing difficulties.
Last updated on 02/01/2010

Ceftizoxime


Trade Names: 
Cefizox®

Possible Uses: 
Prevent or treat bacterial infections.

Possible Side Effects: 
Diarrhea, nausea, vomiting, pain and inflammation at injection site, fever, headache, rash, temporary increase in liver function tests, blurred vision. If patient is allergic, may cause rash, swelling, or breathing difficulties.
Last updated on 02/01/2010

Chlorhexidine


Trade Names: 
Peridex®

Possible Uses: 
Prevent oral infections.

Special Notes: 
Oral rinse: completely rinse toothpaste from mouth, then swish in mouth for 30 seconds and spit out. Do not swallow.

Possible Side Effects: 
Temporary mouth and/or tongue irritation, increased tartar on teeth, metallic taste, stained tongue and/or teeth, nausea, vomiting.
Last updated on 02/01/2010

Cidofovir


Trade Names: 
Vistide®

Possible Uses: 
Use to treat cytomegalovirus infections (CMV). Also used 'off label' to treat BK virus in the bladder.

Drug Interactions: 
when used in higher doses a drug known as probenecid must also be given to protect the kidneys

Possible Side Effects: 
chills, fevers, headaches, hair loss, rash, nausea, vomiting, diarrhea, anemia, neutropenia, weakness, kidney damage, cough, difficulty breathing. Diabetics need to monitor blood glucose as it may be elevated.
Last updated on 02/01/2010

Cimetidine


Trade Names: 
Tagamet®

Possible Uses: 
Decrease acid in the stomach, prevent or treat heartburn and ulcers.

Special Notes: 
Take with or immediately after meals. Take 1 hour before or 2 hours after antacids. Avoid excessive alcohol

Drug Interactions: 
Interacts with some drugs that are metabolized by the liver. Check with your pharmacist.

Possible Side Effects: 
Diarrhea, nausea, vomiting, dizziness, headache, drowsiness.
Last updated on 02/01/2010

Ciprofloxacin


Trade Names: 
Cipro®

Possible Uses: 
Prevent or treat bacterial infection.

Special Notes: 
Take on an empty stomach, 2 hours after meals. Avoid taking any calcium, magnesium, or iron products within two hours of taking this medication. Take entire prescription even if feeling better. Maintain adequate hydration ask your healthcare provider to how much you should take in. Increased sensitivity to sunlight may occur, use sunblock or other protective means while out. Avoid direct sun exposure, Report immediately any signs of skin rash, joint or back pain, or difficulty breathing.

Drug Interactions: 
Avoid calcium supplements, antacids, and dairy products one hour before or two hours after taking.

Possible Side Effects: 
Stomach upset, nausea, vomiting, diarrhea, sensitivity to sunlight, headache, dizziness, change in liver or kidney function (generally temporary). Rarely, may cause seizures. If patient is allergic, may cause breathing difficulties, swelling of face, throat or lips, or rash.
Last updated on 02/01/2010

Cisplatin


Trade Names: 
Platinol®

Possible Uses: 
A chemotherapy drug.

Special Notes: 
Derived from the metal platinum. Maintaining adequate fluid intake to help prevent kidney damage, speak to your healthcare provider of how much to take in. Nausea and vomiting can be severe and can be delayed. Notify your healthcare provider if you feel signs and symptoms of infection.

Possible Side Effects: 
Decreased blood counts, nausea, vomiting, diarrhea, loss of appetite, metallic taste in mouth, mouth sores, tiredness, temporary hair loss, numbness or tingling in hands and feet, loss of potassium and magnesium in blood, ringing in ears, hearing damage, and decreased kidney function. Rarely, allergic type reactions may cause breathing difficulties with swelling of mouth and tongue.
Last updated on 02/01/2010

Cladribine


Trade Names: 
Leustatin®

Alternate Names: 
2-CdA

Possible Uses: 
This agent is chemotherapy. It is used to treat hairy cell leukemia, chronic lymphocytic leukemia, chronic myelogenous leukemia, and non-Hodgkin's lymphomas.

Possible Side Effects: 
Fever, tiredness, headache, rash nausea, vomiting, decrease in infection fighting cells causing increase potential for infections, decrease in your red blood cells which will cause fatigue, decrease in your platlets which will cause increase your risk for bleeding or easy bruising, injection site reactions, infection, rapid heart beats, dizziness, chills, rash, diarrhea, constipation, abdominal pain, breathing diffiuclties
Last updated on 02/01/2010

Clarithromycin


Trade Names: 
Biaxin®

Possible Uses: 
Treat or prevent infection.

Special Notes: 
Finish all medication. Do NOT skip doses

Drug Interactions: 
Interferes with some drugs metabolized by the liver. May be toxic to heart when used with quinidine. Avoid calcium supplements, antacids, and dairy products one hour before or two hours after taking.

Possible Side Effects: 
Diarrhea, abdominal pain and cramping, nausea, vomiting, liver dysfunction, heartbeat irregularity, rash.
Last updated on 02/01/2010

Clindamycin


Trade Names: 
Cleocin®

Possible Uses: 
Prevent or treat bacterial infections.

Special Notes: 
Contact your healthcare provider for severe diarrhea. Do NOT take any over the counter anti-diarrheal medication unless directed by your helathcare provider. Take all the medication given to you, even if you are feeling better.

Drug Interactions: 
Avoid calcium supplements, antacids, and dairy products one hour before or two hours after taking.

Possible Side Effects: 
Diarrhea, rash, nausea, and vomiting. May cause pseudomembranous colitis which causes diarrhea. May predispose patient to a bowel infection called clostridium difficile. If you get diarrhea, do not not take anti-diarrhea medication until you talk with your doctor.
Last updated on 02/01/2010

Clonazepam


Trade Names: 
Klonopin®

Possible Uses: 
Treat or prevent seizures, relieve nerve pain, decrease anxiety.

Drug Interactions: 
Use of other sedatives may have an additive effect.

Possible Side Effects: 
Blurred vision, headache, dry mouth, nausea, vomiting, diarrhea, drowsiness, reduced coordination, difficulty concentrating, breathing difficulties, slow heartbeat, balance problems, depression, confusion. May casue drowsiness. Do NOT operate heavy machinary.
Last updated on 02/01/2010

Clotrimazole


Trade Names: 
Mycelex®

Possible Uses: 
Prevent/control fungal infections in the mouth and throat.

Special Notes: 
Dissolve troche slowly and completely in the mouth. Do not swallow.

Possible Side Effects: 
Change in taste, upset stomach, nausea, vomiting, temporary change in liver function.
Last updated on 02/01/2010

Codeine


Possible Uses: 
Relieve mild to moderate pain.

Possible Side Effects: 
Constipation, confusion, nausea, vomiting, sleepiness, itching, decreased respiration.
Last updated on 02/01/2010

Cyclobenzaprine


Trade Names: 
Flexeril®

Possible Uses: 
Treat muscle spasms or some painful muscle conditions.

Possible Side Effects: 
Drowsiness, dizziness, lightheadedness, fainting, confusion, dry mouth, swelling of face and lips, muscle weakness, blurred vision, problems urinating, problems speaking.
Last updated on 02/01/2010

Cyclophosphamide


Trade Names: 
Cytoxan®
Trade Names: 
Neosar®

Possible Uses: 
Chemotherapy drug.

Possible Side Effects: 
Nausea, vomiting, temporary hair loss, mouth sores, infertility, darkened skin or fingernails, swollen feet or ankles, tiredness, breathing problems, bloody urine, irregular or fast heartbeat, lung disorder (usually reversible). Large doses of the drug may cause bladder irritation which can result in pain and bleeding. MESNA is used to prevent bladder irritation from cyclophosphamide.
Last updated on 02/01/2010

Cyclosporine A


Trade Names: 
Neoral®
Trade Names: 
Sandimune®

Possible Uses: 
In allogeneic transplantation, used to prevent or treat graft-versus-host disease (GVHD).

Drug Interactions: 
Avoid grapefruit juice. Take at the same time each day. There are many drugs that may decrease or increase blood levels. Check with pharmacist.

Possible Side Effects: 
High blood pressure, decreased kidney function, muscle tremor, enlargement of the gums, seizure, acne, leg cramps, abdominal discomfort, diarrhea, nausea, vomiting.
Last updated on 02/01/2010

Cytarabine


Trade Names: 
Cytosar-U®

Alternate Names: 
Cytosine Arabinoside
Alternate Names: 
ara-C

Possible Uses: 
Chemotherapy drug.

Possible Side Effects: 
Nausea, vomiting, diarrhea, rash, temporary hair loss, mouth sores, stomach cramps, loss of appetite, yellow skin or eyes, sensitivity to light, flu-like feeling, temporary liver disorder, breathing difficulties. High doses of this drug can cause confusion, dizziness, and inflammation and pain of the eyes.
Last updated on 02/01/2010

Cytomegalovirus Immune Globulin


Trade Names: 
Cytogam®

Alternate Names: 
CMV-IVIG

Possible Uses: 
Provide a source of antibodies against cytomegalovirus (CMV) infection.

Possible Side Effects: 
Flushing, nausea, vomiting, muscle cramps, back pain, wheezing, sweating, fever, chills.
Last updated on 02/01/2010

Dexamethasone


Trade Names: 
Decadron®
Trade Names: 
Dexasone®
Trade Names: 
Dexone®
Trade Names: 
Cortasta®
Trade Names: 
Hexadrol®

Possible Uses: 
Decrease inflammation, allergic reactions, nausea, vomiting. In allogeneic transplantation, used to prevent or treat graft-versus-host disease.

Possible Side Effects: 
Fluid retention, weight gain, increased blood sugars, increased blood pressure, restlessness, anxiety, trouble sleeping, increased appetite, indigestion, mood changes, acne, thinning of the skin, muscle cramps, dark stools, increased risk of fungal infection.
Last updated on 02/01/2010

Diclofenac


Trade Names: 
Cataflam®
Trade Names: 
Voltaren®

Possible Uses: 
Relieve nerve pain, bone pain and headaches.

Possible Side Effects: 
Headache, nausea and vomiting, stomach cramps, stomach/intestinal bleeding, swelling of feet or legs, weight gain, constipation, diarrhea, dizziness, drowsiness, ringing in ears, blurred visions, skin sensitivity to light, black stools, bloody vomit, decreased urination, yellowing of eyes or skin, breathing difficulties, swelling of face or around eyes, flu-like feeling, rash, itching, reduced kidney function, liver toxicity. Used only when absolutely necessary, and then with great care, due to bleeding risks.
Last updated on 02/01/2010

Ganciclovir


Trade Names: 
Cytovene®

Possible Uses: 
Prevent or treat viral infections, particularly cytomegalovirus.

Possible Side Effects: 
Nausea, vomiting diarrhea, loss of appetite, drowsiness, headache, numbness or tingling in hands or feet, dizziness, nervousness, confusion, strange dreams, fatigue, weakness, rash, flu-like feeling.
Last updated on 02/01/2010

Mycophenolate


Trade Names: 
CellCept®

Possible Uses: 
Used after allogeneic stem cell transplant to prevent graft vs host disease

Drug Interactions: 
The effects of mycophenolate may be decreased by antacids, magnesium salts, metronidazole, cyclosporin. Avoid cat's claw and echinacea

Possible Side Effects: 
abdominal pain, anemia, diarrhea, constipation, fever, high blood pressure, low blood pressure, chest pain, low white blood cell counts, anemia, infections, nausea, vomiting, rash. Possible liver and kidney dysfunction. High blood sugar and high cholestrol levels. Low magnesium, potassium, and calcium levels.
Last updated on 02/01/2010

Prednisone


Trade Names: 
Deltasone®
Trade Names: 
Cortan®
Trade Names: 
Orasone®

Possible Uses: 
Decrease swelling, decrease allergic reactions, control nausea or vomiting. May be used as part of chemotherapy regimen. In allogeneic transplants, used to prevent or treat graft rejection.

Possible Side Effects: 
Fluid retention, weight gain, increase in blood sugars, increase in white cell count, restlessness, anxiety, mood changes, sweating, redness in face, thinning skin, acne, increased hair growth, irregular menstrual periods, black bowel movements, muscle weakness or cramps.
Last updated on 02/01/2010

Prochlorperazine


Trade Names: 
Compazine®

Possible Uses: 
Control nausea and vomiting.

Possible Side Effects: 
Drowsiness, dizziness, blurred vision, muscle spasms, jittery feeling, rash, difficulty urinating, dry mouth, nausea, constipation, rapid heartbeat. Rarely, breathing difficulties or seizures.
Last updated on 02/01/2010

Sucralfate


Trade Names: 
Carafate®

Possible Uses: 
Prevent or treat stomach ulcers, stomatitis or ulcers in the mouth or throat caused by chemotherapy and radiation.

Special Notes: 
Try to separate other medicines from this one by 2 hours Avoid alcohol (includes wine, beer, and liquor).

Drug Interactions: 
Do not take antacids 30 minutes before or after taking this medicine.

Possible Side Effects: 
Constipation, stomach gas, indigestion, dry mouth, nausea, vomiting.
Last updated on 02/01/2010

Supersaturated Calcium Phosphate rinse


Trade Names: 
Caphosol®

Possible Uses: 
Caphosol is indicated for dryness of the mouth or throat (hyposalivation, xerostomia), regardless of the cause and regardless of whether the conditions are temporary or permanent. Caphosol is also indicated as an adjunct to standard oral care in treating the mucositis that may be caused by radiation or high dose chemotherapy.

Possible Side Effects: 
If Caphosol is swallowed accidentally, no adverse effects are expected. There are no known interactions with other medications. Reported side effects have been rare and generally mild.
Last updated on 05/04/2010
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