Welcome to the BMTInfonet Drug Database

This guide lists many of the drugs bone marrow, stem cell and cord blood transplants patients receive during treatment. It explains why they are used and some, but not allAcute lymphoblastic leukemia., of the possible side effects.

This guide should not be used as a substitute for a detailed discussion with your doctor and pharmacist about drugs you are being given. If you experience any side effect after taking the drug, even if they are not noted below, consult your doctor immediately.

Some of the drugs in this guide are also used outside the transplant setting. The descriptions of the drugs in this guide pertain only to their use in bone marrow, stem cell or cord blood transplantation.

If you are searching for a drug used by transplant patients and survivors that is not in this database, please contact us at drugdata@bmtinfonet.org.

This database was compiled under the direction of pharmacists knowledgeable about transplantation, but should not be construed as medical advice. Consult your doctor for information about how each drug might affect you.

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Daclizumab


Trade Names: 
Zenapax®

Possible Uses: 
In allogeneic transplantation, an investigational drug used to treat or prevent graft versus host disease (GVHD).

Special Notes: 
This is a monoclonal antibody. Let your doctor know if you have ever had a monoclonal antibody before.

Possible Side Effects: 
Rash, fever, chills, an increased risk of infection.
Last updated on 02/01/2010

Dapsone


Possible Uses: 
Use to prevent a lung infection known as PCP

Possible Side Effects: 
decreased red cells,facial edema, depression, fever, headache, dizziness, dermatitis, severe skin rash,stomach pain, nausea, vomiting, jaundice,
Last updated on 02/01/2010

Dexamethasone


Trade Names: 
Decadron®
Trade Names: 
Dexasone®
Trade Names: 
Dexone®
Trade Names: 
Cortasta®
Trade Names: 
Hexadrol®

Possible Uses: 
Decrease inflammation, allergic reactions, nausea, vomiting. In allogeneic transplantation, used to prevent or treat graft-versus-host disease.

Possible Side Effects: 
Fluid retention, weight gain, increased blood sugars, increased blood pressure, restlessness, anxiety, trouble sleeping, increased appetite, indigestion, mood changes, acne, thinning of the skin, muscle cramps, dark stools, increased risk of fungal infection.
Last updated on 02/01/2010

Diclofenac


Trade Names: 
Cataflam®
Trade Names: 
Voltaren®

Possible Uses: 
Relieve nerve pain, bone pain and headaches.

Possible Side Effects: 
Headache, nausea and vomiting, stomach cramps, stomach/intestinal bleeding, swelling of feet or legs, weight gain, constipation, diarrhea, dizziness, drowsiness, ringing in ears, blurred visions, skin sensitivity to light, black stools, bloody vomit, decreased urination, yellowing of eyes or skin, breathing difficulties, swelling of face or around eyes, flu-like feeling, rash, itching, reduced kidney function, liver toxicity. Used only when absolutely necessary, and then with great care, due to bleeding risks.
Last updated on 02/01/2010

Dimethylsulfoxide


Alternate Names: 
DMSO

Possible Uses: 
Used to preserve stem cells or bone marrow when frozen.

Possible Side Effects: 
Bad taste in mouth, bad smell, decreased blood pressure when stem cells are re-infused. Rarely, allergic reaction that causes chest or throat tightness and shortness of breath.
Last updated on 02/01/2010

Diphenhydramine


Trade Names: 
Benadryl®

Possible Uses: 
Decrease allergic reaction from some medications, decrease itching, dry up mucous, decrease sinus drainage. This is an anti-histamine

Possible Side Effects: 
Rash, sweating, chills, dry mouth, nose and throat, low blood pressure, head ache, heart palpitation, sedation, drowsiness, dizziness, decreased coordination.
Last updated on 02/01/2010

Diphenoxylate with Atropine


Trade Names: 
Logen®
Trade Names: 
Lomenate®
Trade Names: 
Lomotil®
Trade Names: 
Lonox®
Trade Names: 
Lo-Trol®
Trade Names: 
Nor-Mil®

Possible Uses: 
Used to control diarrhea. Is not available over the counter.

Possible Side Effects: 
Nausea, vomiting, decreased urination, constipation, sweating, itchy skin, slowed breathing, drowsiness, dizziness, restlessness, dry mouth, blurred vision, headache, irregular or fast heartbeat, seizures.
Last updated on 02/01/2010

Docetaxel


Trade Names: 
Taxotere®

Possible Uses: 
A chemotherapy drug.

Special Notes: 
Dexamethasone is required to be taken for 3 days when receiving this drug. It is used to reduce/prevent side effects from docetaxel.

Possible Side Effects: 
Decreased blood counts, weakness, fatigue, mild nausea or vomiting, tingling or pain in arms and/or legs, fluid in arms and/or legs, rash, change in fingernails (usually darkening and yellowing), temporary hair loss, irritation at injection site. Rarely, separation of nails from fingers. Nails regrow when drug is discontinued.
Last updated on 02/01/2010

Doxepin


Trade Names: 
Adapin®
Trade Names: 
Sinequan®

Possible Uses: 
Relieve depression, treat pain associated with the nerves.

Possible Side Effects: 
Dry mouth, constipation, confusion, drowsiness, dizziness, nausea, blurred vision, sensitivity to sunlight, low blood pressure, heart rhythm changes, hives, swelling of face, lips or tongues, difficulty urinating, hallucinations.
Last updated on 02/01/2010

Doxorubicin


Trade Names: 
Doxil®
Trade Names: 
Adriamycin®
Trade Names: 
Rubex®

Possible Uses: 
A chemotherapy drug.

Drug Interactions: 
Inj. dexrazoxane can be given to prevent heart toxicities of doxorubicin.

Possible Side Effects: 
Decreased blood counts, temporary hair loss, mouth sores, loss of appetite, flu-like symptoms, heart damage, breathing difficulties, swelling in legs and feet, rash, itching, nausea, vomiting, diarrhea. May cause temporary orange or red color in urine and secretions (tears, mucous). When doxorubicin leaks outside the vein severe skin damage can occur.
Last updated on 02/01/2010

Fentanyl


Trade Names: 
Actiq®
Trade Names: 
Duragesic®
Trade Names: 
Sublimaze®
Trade Names: 
Onsolis®

Possible Uses: 
Relieve severe or long-term pain.

Possible Side Effects: 
Constipation, nausea, vomiting, drowsiness, confusion, dry mouth, stomach pain, rash, itching, swelling, breathing difficulties, irregular heartbeat, chest pain.
Last updated on 02/01/2010

Fluconazole


Trade Names: 
Diflucan®

Possible Uses: 
Prevent or treat fungal infections.

Drug Interactions: 
This drug may interfer with many other drugs. Please check with your pharmacist

Possible Side Effects: 
Nausea, vomiting, diarrhea, rash, itching, headache, stomach upset/pain, loss of appetite, dark colored urine, pale colored bowel movements, fatigue, yellow skin or eyes, change in liver function.
Last updated on 02/01/2010

Hydromorphone


Trade Names: 
Dilaudid®

Possible Uses: 
Relieve severe pain.

Possible Side Effects: 
Shortness of breath, rash, itching, slow, fast or irregular heartbeat, difficulty urinating, constipation, nausea, vomiting, loss of appetite, drowsiness, confusion, dizziness, headache, blurred vision, sweating, cold or clammy skin.
Last updated on 02/01/2010

Meperidine


Trade Names: 
Demerol®

Possible Uses: 
Relieve moderate to severe pain, relieve or prevent chills caused by platelet transfusions or amphotericin B.

Special Notes: 
As a pain reliever it is not useful for long lasting pain. Do not use if you have kidney problems.

Possible Side Effects: 
Dizziness, drowsiness, itching, constipation, nausea, vomiting, diarrhea, nervousness, irritability, confusion, hallucinations, tremors, seizures, difficulty urinating, slow, fast or irregular heartbeat, rash, breathing difficulties.
Last updated on 02/01/2010

Phenytoin


Trade Names: 
Dilantin®

Possible Uses: 
Prevent or treat seizures. Also used with other pain medications to help relieve nerve pain.

Possible Side Effects: 
Sleepiness, reduced coordination, low blood pressure, involuntary eye or body movement, confusion, rash, flu-like feeling, loss of appetite, nausea, vomiting, nervousness, trouble sleeping, constipation, excess hair growth, thickening of gums. Rarely, causes severe burn like damage to skin called Stevens-Johnson syndrome. If you notice a rash that starts to get worse after being started on phenytoin, notify your doctor immediately.
Last updated on 02/01/2010

Prednisone


Trade Names: 
Deltasone®
Trade Names: 
Cortan®
Trade Names: 
Orasone®

Possible Uses: 
Decrease swelling, decrease allergic reactions, control nausea or vomiting. May be used as part of chemotherapy regimen. In allogeneic transplants, used to prevent or treat graft rejection.

Possible Side Effects: 
Fluid retention, weight gain, increase in blood sugars, increase in white cell count, restlessness, anxiety, mood changes, sweating, redness in face, thinning skin, acne, increased hair growth, irregular menstrual periods, black bowel movements, muscle weakness or cramps.
Last updated on 02/01/2010
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