Welcome to the BMTInfonet Drug Database

This guide lists many of the drugs bone marrow, stem cell and cord blood transplants patients receive during treatment. It explains why they are used and some, but not allAcute lymphoblastic leukemia., of the possible side effects.

This guide should not be used as a substitute for a detailed discussion with your doctor and pharmacist about drugs you are being given. If you experience any side effect after taking the drug, even if they are not noted below, consult your doctor immediately.

Some of the drugs in this guide are also used outside the transplant setting. The descriptions of the drugs in this guide pertain only to their use in bone marrow, stem cell or cord blood transplantation.

If you are searching for a drug used by transplant patients and survivors that is not in this database, please contact us at drugdata@bmtinfonet.org.

This database was compiled under the direction of pharmacists knowledgeable about transplantation, but should not be construed as medical advice. Consult your doctor for information about how each drug might affect you.

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Amphotericin B


Trade Names: 
Abelcet®
Trade Names: 
AmBisome®
Trade Names: 
Amphotec®
Trade Names: 
Fungizone®

Possible Uses: 
Prevent or treat fungal infections.

Possible Side Effects: 
Fever, chills, muscle shaking, nausea, vomiting, decreased electrolytes (especially potassium and magnesium), decreased blood pressure, shortness of breath, decreased kidney function, diarrhea, rash, and anemia.
Last updated on 02/01/2010

Ceftazidime


Trade Names: 
Ceftaz®
Trade Names: 
Fortaz®
Trade Names: 
Tazidime®

Possible Uses: 
Prevent or treat bacterial infections.

Possible Side Effects: 
Diarrhea, nausea, vomiting, pain and inflammation at injection site, fever, headache, rash, temporary increase in liver function tests, blurred vision. If patient is allergic, may cause rash, swelling, or breathing difficulties.
Last updated on 02/01/2010

Cyclobenzaprine


Trade Names: 
Flexeril®

Possible Uses: 
Treat muscle spasms or some painful muscle conditions.

Possible Side Effects: 
Drowsiness, dizziness, lightheadedness, fainting, confusion, dry mouth, swelling of face and lips, muscle weakness, blurred vision, problems urinating, problems speaking.
Last updated on 02/01/2010

Famciclovir


Trade Names: 
Famvir®

Possible Uses: 
Treat viral infections.

Possible Side Effects: 
Nausea, vomiting, diarrhea, headache, tiredness, rash, increase in liver enzymes, itching. If patient is allergic, may cause breathing difficulties, tightness in chest, swelling in face.
Last updated on 02/01/2010

Famotidine


Trade Names: 
Pepcid®

Possible Uses: 
Reduce acid in stomach, treat or prevent ulcers or reflux.

Possible Side Effects: 
Headache, dizziness, diarrhea, constipation, rash.
Last updated on 02/01/2010

Fentanyl


Trade Names: 
Actiq®
Trade Names: 
Duragesic®
Trade Names: 
Sublimaze®
Trade Names: 
Onsolis®

Possible Uses: 
Relieve severe or long-term pain.

Possible Side Effects: 
Constipation, nausea, vomiting, drowsiness, confusion, dry mouth, stomach pain, rash, itching, swelling, breathing difficulties, irregular heartbeat, chest pain.
Last updated on 02/01/2010

Filgrastim


Trade Names: 
Neupogen®

Alternate Names: 
G-CSF

Possible Uses: 
Increase the number of stem cells available for harvest in the bloodstream; speed recovery of white blood cell counts after transplant.

Possible Side Effects: 
Bone pain, nausea, loss of appetite, fever, chills, sore throat, rash, itching, swelling in face, lips or throat, breathing difficulties, fast or irregular heartbeat, pain at injection site, enlarged spleen.
Last updated on 02/01/2010

Flt-3 ligand


Possible Uses: 
An investigational drug that increases the production of dendritic cells. May also increase the number of stem cells available for harvest when used with G-CSF or GM-CSF.

Possible Side Effects: 
Pain at injection site, may be others not yet known.
Last updated on 02/01/2010

Fluconazole


Trade Names: 
Diflucan®

Possible Uses: 
Prevent or treat fungal infections.

Drug Interactions: 
This drug may interfer with many other drugs. Please check with your pharmacist

Possible Side Effects: 
Nausea, vomiting, diarrhea, rash, itching, headache, stomach upset/pain, loss of appetite, dark colored urine, pale colored bowel movements, fatigue, yellow skin or eyes, change in liver function.
Last updated on 02/01/2010

Fludarabine


Trade Names: 
Fludara®

Possible Uses: 
Use to treat Chronic lypmhocytic leukemia (CLL), non-Hodgkin's lymphomas, and reduced instensity conditioning regimens prior to allogeneic stem cell transplant

Special Notes: 
Can be given IV or orally

Possible Side Effects: 
edema, rash, mild nausea/vomiting, diarrhea, GI bleeding, myelosuppression, anemia, low platelets, weakness,cough, respiratory infections,
Last updated on 02/01/2010

Fluoxetine


Trade Names: 
Prozac®

Possible Uses: 
Treat depression or nerve-related pain.

Possible Side Effects: 
Rash, headaches, drowsiness, nausea, diarrhea, insomnia, weight loss, nervousness, dry mouth, sweating, shakiness, increased need to urinate, change in taste, fast heartbeat, breathing difficulties.
Last updated on 02/01/2010

Foscarnet


Trade Names: 
Foscavir®

Possible Uses: 
Prevent or treat viral infections.

Possible Side Effects: 
Headache, fatigue, nausea, vomiting, diarrhea, loss of appetite, confusion, nervousness, rash, seizures, flu-like feelings, pain or tingling or numbness in hands or feet or around the mouth, fever, change in kidney function, decrease in calcium and other minerals in the body.
Last updated on 02/01/2010

Furosemide


Trade Names: 
Lasix®

Possible Uses: 
Increase urine production and decrease water in body.

Possible Side Effects: 
Decreased potassium, decreased blood pressure, dizziness, rash, itching, decreased sodium, chloride and magnesium. Persons allergic to sulfa drugs may have an allergic reaction.
Last updated on 02/01/2010

Methotrexate


Trade Names: 
Folex PFS®
Trade Names: 
Rheumatrex®

Alternate Names: 
MTX

Possible Uses: 
Chemotherapy drug used in many cancers. Interfers with the way the body uses folic acid. Often used after a transplant to prevent graft vs host disease.

Drug Interactions: 
probeneicd, peniccillins. Folic aid, NSAIDs,

Possible Side Effects: 
Nausea, vomiting, diarrhea, temporary hair loss, mouth sores, headache, fever, chills, sore throat, loss of appetite, breathing difficulties, rash, itching, yellow eyes or skin, dark urine, decreased urine output.
Last updated on 02/01/2010

Metronidazole


Trade Names: 
Flagyl®

Possible Uses: 
Prevent or treat bacterial infection.

Drug Interactions: 
Avoid the use of alcohol when using this drug. Use with alcohol may cause reactions including sweating, nausea, vomiting, heart palpitations, headache, and flushing. May interact with warfarin (Coumadin), resulting in increased risk of bleeding.

Possible Side Effects: 
Nausea, vomiting, diarrhea, headache, dark colored urine, stomach upset, metallic taste, itching, rash.
Last updated on 02/01/2010

Ofloxacin


Trade Names: 
Floxin®

Possible Uses: 
Prevent or treat bacterial infections.

Drug Interactions: 
Avoid calcium supplements, antacids, and dairy products one hour before or two hours after taking.

Possible Side Effects: 
Nausea, diarrhea, stomach upset, vomiting, headache, dizziness, sensitivity to sunlight, rash.
Last updated on 02/01/2010
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