Welcome to the BMTInfonet Drug Database

This guide lists many of the drugs bone marrow, stem cell and cord blood transplants patients receive during treatment. It explains why they are used and some, but not allAcute lymphoblastic leukemia., of the possible side effects.

This guide should not be used as a substitute for a detailed discussion with your doctor and pharmacist about drugs you are being given. If you experience any side effect after taking the drug, even if they are not noted below, consult your doctor immediately.

Some of the drugs in this guide are also used outside the transplant setting. The descriptions of the drugs in this guide pertain only to their use in bone marrow, stem cell or cord blood transplantation.

If you are searching for a drug used by transplant patients and survivors that is not in this database, please contact us at drugdata@bmtinfonet.org.

This database was compiled under the direction of pharmacists knowledgeable about transplantation, but should not be construed as medical advice. Consult your doctor for information about how each drug might affect you.

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Filgrastim


Trade Names: 
Neupogen®

Alternate Names: 
G-CSF

Possible Uses: 
Increase the number of stem cells available for harvest in the bloodstream; speed recovery of white blood cell counts after transplant.

Possible Side Effects: 
Bone pain, nausea, loss of appetite, fever, chills, sore throat, rash, itching, swelling in face, lips or throat, breathing difficulties, fast or irregular heartbeat, pain at injection site, enlarged spleen.
Last updated on 02/01/2010

Gabapentin


Trade Names: 
Neurontin®

Possible Uses: 
Prevent or treat seizures, treat nerve pain.

Possible Side Effects: 
Tiredness, dizziness, unsteady feeling, nausea, blurred vision.
Last updated on 02/01/2010

Ganciclovir


Trade Names: 
Cytovene®

Possible Uses: 
Prevent or treat viral infections, particularly cytomegalovirus.

Possible Side Effects: 
Nausea, vomiting diarrhea, loss of appetite, drowsiness, headache, numbness or tingling in hands or feet, dizziness, nervousness, confusion, strange dreams, fatigue, weakness, rash, flu-like feeling.
Last updated on 02/01/2010

Gentamicin


Trade Names: 
Garamycin®

Possible Uses: 
Prevent or treat bacterial infection.

Possible Side Effects: 
Nausea, diarrhea, upset stomach, muscle weakness, twitching, decreased kidney function, dizziness, ringing in ears, hearing trouble. If patient is allergic, may cause breathing difficulties, rash, swelling of face, throat or lips.
Last updated on 02/01/2010

Granisetron


Trade Names: 
Kytril®

Possible Uses: 
Control nausea and vomiting caused by chemotherapy, radiation, or after surgery

Possible Side Effects: 
Headache, diarrhea, constipation, skin rash.
Last updated on 02/01/2010

Imatinib


Trade Names: 
Gleevec®

Possible Uses: 
CML (chronic myelogenous leukemia), Philadelphia + ALL, Gastrointestinal stromal tumors (GIST)

Special Notes: 
take with food and a full glass of water to decrease nausea and stomach upset

Drug Interactions: 
possible interactions with warfarin, phenytoin, carbamazepine, rifampin, phenobarbital, ketoconazole, itraconazole, erythromycin, clarithromycin, and St. John's wort

Possible Side Effects: 
nausea, fluid retention (especially around eyes and ankles), weight gain, diarrhea, neutropenia, thrombocytopenia, may alter liver function testing, skin rashes, which can be severe
Last updated on 02/01/2010

Immune Globulin


Trade Names: 
Gamimune N®
Trade Names: 
Gammagard®
Trade Names: 
Gammar-IV®
Trade Names: 
Iveegam®
Trade Names: 
PolyGam®
Trade Names: 
Sandoglobulin®
Trade Names: 
Venoglobulin®

Alternate Names: 
IGG
Alternate Names: 
IVIG

Possible Uses: 
Prevent or treat infection while immune system is weak.

Special Notes: 
A product derived from human blood collections.

Possible Side Effects: 
Fever, chills, allergic reaction, rash, flushing, tightness in chest, dizziness, nausea, vomiting, increased blood pressure, headache, fatigue, pain in back, hip or joints, kidney damage.
Last updated on 02/01/2010

Sargramostim


Trade Names: 
Leukine®

Alternate Names: 
GM-CSF

Possible Uses: 
Speed recovery of white blood cell count after transplant. Also used to move stem cells from bone marrow into the bloodstream prior to a stem cell harvest.

Possible Side Effects: 
Reaction at injection site, chills, fever, bone pain, muscle ache, rash, itching, swelling, fatigue, headache, flushing, nausea, vomiting, diarrhea. Rarely, breathing difficulties, fast or slow or irregular heartbeat.
Last updated on 02/01/2010
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