Welcome to the BMTInfonet Drug Database

This guide lists many of the drugs bone marrow, stem cell and cord blood transplants patients receive during treatment. It explains why they are used and some, but not allAcute lymphoblastic leukemia., of the possible side effects.

This guide should not be used as a substitute for a detailed discussion with your doctor and pharmacist about drugs you are being given. If you experience any side effect after taking the drug, even if they are not noted below, consult your doctor immediately.

Some of the drugs in this guide are also used outside the transplant setting. The descriptions of the drugs in this guide pertain only to their use in bone marrow, stem cell or cord blood transplantation.

If you are searching for a drug used by transplant patients and survivors that is not in this database, please contact us at drugdata@bmtinfonet.org.

This database was compiled under the direction of pharmacists knowledgeable about transplantation, but should not be construed as medical advice. Consult your doctor for information about how each drug might affect you.

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Cyclosporine A


Trade Names: 
Neoral®
Trade Names: 
Sandimune®

Possible Uses: 
In allogeneic transplantation, used to prevent or treat graft-versus-host disease (GVHD).

Drug Interactions: 
Avoid grapefruit juice. Take at the same time each day. There are many drugs that may decrease or increase blood levels. Check with pharmacist.

Possible Side Effects: 
High blood pressure, decreased kidney function, muscle tremor, enlargement of the gums, seizure, acne, leg cramps, abdominal discomfort, diarrhea, nausea, vomiting.
Last updated on 02/01/2010

Doxepin


Trade Names: 
Adapin®
Trade Names: 
Sinequan®

Possible Uses: 
Relieve depression, treat pain associated with the nerves.

Possible Side Effects: 
Dry mouth, constipation, confusion, drowsiness, dizziness, nausea, blurred vision, sensitivity to sunlight, low blood pressure, heart rhythm changes, hives, swelling of face, lips or tongues, difficulty urinating, hallucinations.
Last updated on 02/01/2010

Fentanyl


Trade Names: 
Actiq®
Trade Names: 
Duragesic®
Trade Names: 
Sublimaze®
Trade Names: 
Onsolis®

Possible Uses: 
Relieve severe or long-term pain.

Possible Side Effects: 
Constipation, nausea, vomiting, drowsiness, confusion, dry mouth, stomach pain, rash, itching, swelling, breathing difficulties, irregular heartbeat, chest pain.
Last updated on 02/01/2010

Hydrocortisone


Trade Names: 
Solu-cortef®

Possible Uses: 
Decrease inflammation, decrease or stop allergic reactions, decrease nausea and vomiting. In allogeneic transplants, may be used to treat or prevent graft-versus-host disease.

Possible Side Effects: 
Fluid retention, weight gain, increased blood sugars, increased blood pressure, restlessness, anxiety, trouble sleeping, increased appetite, indigestion, mood changes, acne, thinning of the skin, muscle cramps, dark stools, increased risk of fungal infection.
Last updated on 02/01/2010

Immune Globulin


Trade Names: 
Gamimune N®
Trade Names: 
Gammagard®
Trade Names: 
Gammar-IV®
Trade Names: 
Iveegam®
Trade Names: 
PolyGam®
Trade Names: 
Sandoglobulin®
Trade Names: 
Venoglobulin®

Alternate Names: 
IGG
Alternate Names: 
IVIG

Possible Uses: 
Prevent or treat infection while immune system is weak.

Special Notes: 
A product derived from human blood collections.

Possible Side Effects: 
Fever, chills, allergic reaction, rash, flushing, tightness in chest, dizziness, nausea, vomiting, increased blood pressure, headache, fatigue, pain in back, hip or joints, kidney damage.
Last updated on 02/01/2010

Itraconazole


Trade Names: 
Sporonox®

Possible Uses: 
Prevent or treat fungal infection.

Drug Interactions: 
This drug may interfer with many drugs. Please check with your pharmacist

Possible Side Effects: 
Upset stomach, nausea, vomiting, diarrhea, headache, dizziness, drowsiness, yellow skin or eyes, dark colored urine, clay colored bowel movements, rash, itching.
Last updated on 02/01/2010

Methylprednisolone


Trade Names: 
Medrol®
Trade Names: 
Solu-Medrol®

Possible Uses: 
Decrease swelling and allergic reactions, control nausea and vomiting, or may be used as part of a chemotherapy regimen. In allogeneic transplants, used to prevent graft rejection.

Possible Side Effects: 
Fluid retention, weight gain, increase in blood sugar, increase in white cell count, restlessness, anxiety, mood changes, sweating, redness in face, thinning skin, acne, increased hair growth, irregular menstrual periods, black bowel movements, muscle weakness or cramps.
Last updated on 02/01/2010

Pilocarpine


Trade Names: 
Salagen®

Possible Uses: 
Increase saliva production.

Possible Side Effects: 
Increased sweating. Occasionally, a fast heart rate.
Last updated on 02/01/2010

Quinine


Trade Names: 
Quinamm®
Trade Names: 
Quindan®
Trade Names: 
Quiphile®
Trade Names: 
Q-vel®
Trade Names: 
Strema®

Possible Uses: 
Relieve leg cramps.

Special Notes: 
This drug is not approved or available over the counter to treat leg cramps.

Drug Interactions: 
May interfere with the heart medication quinidine.

Possible Side Effects: 
Headache, nausea, upset stomach, ringing in ears, loss of appetite, itching, swelling, vomiting, stomach cramps, blurred vision, irregular heartbeat, chest pain. If patient is allergic, may cause breathing difficulties, rash, fever, chills, swelling.
Last updated on 02/01/2010

Sargramostim


Trade Names: 
Leukine®

Alternate Names: 
GM-CSF

Possible Uses: 
Speed recovery of white blood cell count after transplant. Also used to move stem cells from bone marrow into the bloodstream prior to a stem cell harvest.

Possible Side Effects: 
Reaction at injection site, chills, fever, bone pain, muscle ache, rash, itching, swelling, fatigue, headache, flushing, nausea, vomiting, diarrhea. Rarely, breathing difficulties, fast or slow or irregular heartbeat.
Last updated on 02/01/2010

Sirolimus


Trade Names: 
Rapamune®

Possible Uses: 
Used during allogeneic transplant to prevent graft vs host disease. Dose may vary depending on blood levels of the drug.

Drug Interactions: 
This drug is dosed to achieve a specific blood level. Many drugs may decrease or increase these levels, please check with your pharmacist.

Possible Side Effects: 
peripheral edema, high blood pressure, chest pain, fever, headache, pain, insomnia, acne, high triglycerides, high cholestrol, low potassium and phosphorus,diarrhea, constipation, Nausea, vomiting, weight gain, anemia, and low platelets. Difficulty breathing, respiratory infections, and kidney damage.
Last updated on 02/01/2010

Sucralfate


Trade Names: 
Carafate®

Possible Uses: 
Prevent or treat stomach ulcers, stomatitis or ulcers in the mouth or throat caused by chemotherapy and radiation.

Special Notes: 
Try to separate other medicines from this one by 2 hours Avoid alcohol (includes wine, beer, and liquor).

Drug Interactions: 
Do not take antacids 30 minutes before or after taking this medicine.

Possible Side Effects: 
Constipation, stomach gas, indigestion, dry mouth, nausea, vomiting.
Last updated on 02/01/2010

Trimethoprim/sulfamethoxazole


Trade Names: 
Bactrim®
Trade Names: 
Bactrim DS®
Trade Names: 
Septra®
Trade Names: 
Uroplus®

Alternate Names: 
TMP/SMX

Possible Uses: 
Prevent or treat bacterial infections.

Possible Side Effects: 
Rash, nausea, vomiting, diarrhea, stomach upset, decreased blood counts, change in kidney or liver function. If patient is allergic, may cause breathing difficulties, swelling of face, throat or lips.
Last updated on 02/01/2010
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