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zoledronic acid


Trade Names: 
Zometa®
Trade Names: 
Reclast®

Possible Uses: 
Used to treat high calcium levels due to malignancy. Other uses include preventing/treating metastatic bone lesions for multiple myeloma patients and patients with solid tumors. Recently approved for treatment of osteoporosis

Special Notes: 
Patients should be taking a daily calcium supplement and multivitamin containing Vitamin D (if dietary intake is inadequate)

Drug Interactions: 
Thalidomide, and Ibuprofen type drugs, may increase the effects of zoledronic acid.

Possible Side Effects: 
Acute reaction within 3 days: fever, muscle or bone aches, flu-like symptoms. Leg edema, hypotension, fatigue, headache, dizziness, insomnia, hair loss, rash, nausea, constipation, vomiting, diarrhea, stomach pain, low white blood count, anemia, bone pain, weakness, decreased renal function.
Last updated on 02/01/2010